Welcome to the Shin Lab!
We study host-pathogen interactions.
In the Shin Lab at the University of Pennsylvania, we are interested in uncovering innate immune mechanisms used by the host to defend itself against bacterial pathogens and how bacterial pathogens evade host immunity to cause disease.
Our most recent work:
Vázquez Marrero, V. R., Doerner, J., Wodzanowski, K. A., Zhang, J., Lu, A., Boyer, F. D., Vargas, I., Hossain, S., Kammann, K. B., Dresler, M. V., & Shin, S. (2025). Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection. mBio, 16(7), e0125725. https://doi.org/10.1128/mbio.01257-25
Our funding:
