Publications

Vázquez Marrero, V. R., Doerner, J., Wodzanowski, K. A., Zhang, J., Lu, A., Boyer, F. D., Vargas, I., Hossain, S., Kammann, K. B., Dresler, M. V., & Shin, S. (2025). Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection. mBio, 16(7), e0125725. https://doi.org/10.1128/mbio.01257-25

Vázquez Marrero VR, Dresler M, Haggadone MD, Lu A, Shin S. 2025. GM-CSF engages multiple signaling pathways to enhance pro-inflammatory cytokine responses in human monocytes during Legionella infection. Infect Immun93:e00565-24.https://doi.org/10.1128/iai.00565-24

S. Poddar*, S. D. Chauvin*, C. H. Archer*, W. Qian*, J. A. Castillo-Badillo, X. Yin, W. M. Disbennett, C. A. Miner, J. A. Holley, T. V. Naismith, W. A. Stinson, X. Wei, Y. Ning, J. Fu, T. A. Ochoa, N. Surve, S. A. Zaver, K. A. Wodzanowski, K. R. Balka, R. Venkatraman, C. Liu, K. Rome, W. Bailis, Y. Shiba, S. Cherry, S. Shin, C. F. Semenkovich, D. De Nardo, S. Yoh, E. D. O. Roberson, S. K. Chanda, D. J. Kast, J. J. Miner, ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation. Cell (2025), doi:10.1016/j.cell.2025.01.027. *co-first authors

Grayczyk, J. P.^, Liu, L.^, Egan, M. S., Aunins, E., Wynosky-Dolfi, M. A., Canna, S. W., Minn, A. J., Shin, S.*, & Brodsky, I. E.* (2024). TLR priming licenses NAIP inflammasome activation by immunoevasive ligands. Proceedings of the National Academy of Sciences of the United States of America, 121(48), e2412700121. Notes: ^co-first authors; *co-corresponding authors.

Nataraj, N. M., Sillas, R. G., Herrmann, B. I., Shin, S.*, & Brodsky, I. E.* (2024). Blockade of IKK signaling induces RIPK1-independent apoptosis in human macrophages. PLoS pathogens, 20(8), e1012469. Notes: *co-corresponding authors.

Omo-Lamai S, Wang Y, Patel MN, Essien EO, Shen M, Majumdar A, Espy C, Wu J, Channer B, Tobin M, Murali S, Papp TE, Maheshwari R, Wang L, Chase LS, Zamora ME, Arral ML, Marcos-Contreras OA, Myerson JW, Hunter CA, Tsourkas A, Muzykantov V, Brodsky I, Shin S, Whitehead KA, Gaskill P, Discher D, Parhiz H, Brenner JS. (2024). Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects. bioRxiv : the preprint server for biology, 2024.04.16.589801.

Hofstaedter, C. E., O'Keefe, I. P., Met, C. M., Wu, L., Vanderwoude, J., Shin, S., Diggle, S. P., Riquelme, S. A., Rasko, D. A., Doi, Y., Harro, J. M., Kopp, B. T., & Ernst, R. K. (2024). Pseudomonas aeruginosa Lipid A Structural Variants Induce Altered Immune Responses. American journal of respiratory cell and molecular biology, 71(2), 207–218. https://doi.org/10.1165/rcmb.2024-0059OC

Hartland, E. L., & Shin, S. (2024). Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence. Current opinion in immunology, 86, 102411. https://doi.org/10.1016/j.coi.2024.102411

Matsuda, R.^, Sorobetea, D.^, Zhang, J.^, Peterson, S. T., Grayczyk, J.P., Yost, W., Apenes, N., Kovalik, M.E., Herrmann, B., O'Neill, R.J., Bohrer, A.C., Lanza, M., Assenmacher, C.-A., Mayer-Barber, K.D., Shin, S.*, Brodsky, I.E.*: A TNF-IL-1 circuit controls Yersinia within intestinal pyogranulomas. Journal of Experimental Medicine in press, 2024 Notes: ^co-first authors; *co-corresponding authors.

Akuma, D.C.^, Wodzanowski, K.A.^, Schwartz Wertman, R.^, Exconde, P.M., Vázquez Marrero, V.R., Odunze, C.E., Grubaugh, D., Shin, S.*, Taabazuing, C.*, Brodsky, I.E.*: Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS. eLife 13: e83725, 2024 Notes: ^co-first authors; *co-corresponding authors.

Bass, A. R., Egan, M. S., Alexander-Floyd, J.*, Lopes Fischer, N.*, Doerner, J., & Shin, S. (2023) Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation. mBio, 0(0), e01707-01723. https://doi.org/doi:10.1128/mbio.01707-23. Notes: *co-third authors

Zhang, J., Brodsky, I.E.*, and Shin, S.*: Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cells. mBio e0131023, 2023. Notes: *co-corresponding authors

Grayczyk, J.P., Egan, M.S., Liu, L., Aunins, E., Wynoski-Dolfi, M.A., Canna, S., Minn, A.J., Shin, S.*, and Brodsky, I.E.*: TLR priming licenses NAIP inflammasome activation by immunoevasive ligands. bioRxiv Page: doi: https://doi.org/10.1101/2023.05.04.539437, 2023 Notes: *co-corresponding authors.

Exconde, P.M.*, Hernandez-Chavez, C.*, Bourne, C.M., Richards, R.M., Bray, M.B.,Lopez, J.L., Srivastava, T., Egan, M.S., Zhang, J., Yoo, W., Shin, S., Discher, B.M., Taabazuing, C.Y.: The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases. Cell Reports 42(12): 113581, 2023. Notes: *co-first authors

Egan, M. S., O'Rourke, E. A., Mageswaran, S. K., Zuo, B., Martynyuk, I., Demissie, T., Hunter, E. N., Bass, A. R., Chang, Y.-W., Brodsky, I. E., & Shin, S. (2023). Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages. bioRxiv, 2023.2007.2017.549348. https://doi.org/10.1101/2023.07.17.549348 

Boyer, M. A., Lopes Fischer, N., & Shin, S.. (2023). TNF and type I IFN induction of the IRG1-itaconate pathway restrictsCoxiella burnetiireplication within mouse macrophages. bioRxiv https://doi.org/10.1101/2023.07.07.548079

Nataraj, N. M., Herrmann, B., Shin, S.*, & Brodsky, I. E.* (2023). Blockade of IKK signaling induces RIPK1-independent apoptosis in human cells. bioRxiv https://doi.org/10.1101/2023.06.20.545781. Notes: *co-corresponding authors

Pollock, T. Y., Vázquez Marrero, V. R., Brodsky, I. E., & Shin, S. (2023). TNF licenses macrophages to undergo rapid caspase-1, -11, and -8-mediated cell death that restricts Legionella pneumophila infection. PLoS pathogens, 19(6), e1010767. Advance online publication. https://doi.org/10.1371/journal.ppat.1010767

Egan, M.S.*, Zhang, J.*, and Shin, S.: Human and mouse NAIP/NLRC4 inflammasome responses to bacterial infection. Current Opinion in Microbiology 73: 102298, 2023. Notes: co-first authors

Zhang, J., Brodsky, I.E.*, and Shin, S.*: Yersinia Type III-Secreted Effectors Subvert Caspase-4-dependent Inflammasome Activation in Human Cells. bioRxiv Page: doi: https://doi.org/10.1101/2023.01.24.525473, 2023 Notes: *co-corresponding authors

Lopes Fischer, N., Boyer, M. A., Bradley, W. P., Spruce, L. A., Fazelinia, H., & Shin, S.. (2022). A Coxiella burnetii effector interacts with the host PAF1 complex and suppresses the innate immune response. bioRxiv doi: https://doi.org/10.1101/2022.04.20.488957

Alexander-Floyd J^, Bass AR^, Harberts EM^, Grubaugh D, Buxbaum JD, Brodsky IE, Ernst RK*, Shin S.* Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation. Infect Immun. 2022 Aug 18;90(8):e0020822. doi: 10.1128/iai.00208-22. Epub 2022 Jul 14. PubMed PMID: 35862709; PubMed Central PMCID: PMC9387229. Notes: ^co-first authors; *co-corresponding authors

Harberts EM^, Grubaugh D^, Akuma DC, Shin S, Ernst RK*, Brodsky IE.* Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11. Infect Immun. 2022 Aug 18;90(8):e0020122. doi: 10.1128/iai.00201-22. Epub 2022 Jul 14. PubMed PMID: 35862717; PubMed Central PMCID: PMC9387250. Notes: ^co-first authors; *co-corresponding authors

Naseer N, Zhang J, Bauer R, Constant DA, Nice TJ, Brodsky IE, Rauch I*, Shin S.* Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells. Infect Immun. 2022 Jul 21;90(7):e0066321. doi: 10.1128/iai.00663-21. Epub 2022 Jun 9. PubMed PMID: 35678562; PubMed Central PMCID: PMC9302179. Notes: *co-corresponding authors

Naseer N*, Egan MS*, Reyes Ruiz VM*, Scott WP, Hunter EN, Demissie T, Rauch I, Brodsky IE, Shin S. Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication. PLoS Pathog. 2022 Jan;18(1):e1009718. doi: 10.1371/journal.ppat.1009718. eCollection 2022 Jan. PubMed PMID: 35073381; PubMed Central PMCID: PMC8812861. Notes: *co-first authors

Lam LKM, Murphy S, Kokkinaki D, Venosa A, Sherrill-Mix S, Casu C, Rivella S, Weiner A, Park J, Shin S, Vaughan AE, Hahn BH, Odom John AR, Meyer NJ, Hunter CA, Worthen GS, Mangalmurti NS. DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia. Sci Transl Med. 2021 Oct 20;13(616):eabj1008. doi: 10.1126/scitranslmed.abj1008. Epub 2021 Oct 20. PubMed PMID: 34669439; PubMed Central PMCID: PMC9065924.

Campos JS, Wherry EJ, Shin S, Ortiz-Carpena JF. Challenging systemic barriers to promote the inclusion, recruitment, and retention of URM faculty in STEM. Cell Host Microbe. 2021 Jun 9;29(6):862-866. doi: 10.1016/j.chom.2021.04.001. Epub 2021 May 4. PubMed PMID: 33951460.

Lopes Fischer N., Shin S, Brodsky IE. Jack-of-all-trades: itaconate tolerizes NLRP3 inflammasome activation. Cell Rep. 2021 Mar 9;34(10):108855. doi: 10.1016/j.celrep.2021.108855. PubMed PMID: 33691120

Liu X, Boyer MA, Holmgren AM, Shin S. Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation. Cell Host Microbe. 2020 Nov 11;28(5):683-698.e6. doi: 10.1016/j.chom.2020.07.019. Epub 2020 Aug 24. PubMed PMID: 32841604; PubMed Central PMCID: PMC9339267.

Liu X, Shin S. Listening In: Plasmacytoid DC, Monocyte-Derived DC, and Neutrophil Crosstalk in Antifungal Defense. Cell Host Microbe. 2020 Jul 8;28(1):9-11. doi: 10.1016/j.chom.2020.06.015. PubMed PMID: 32645355; PubMed Central PMCID: PMC9326893.

Lopes Fischer N., Naseer N, Shin S, Brodsky IE. Publisher Correction: Effector-triggered immunity and pathogen sensing in metazoans. Nat Microbiol. 2020 Mar;5(3):528. doi: 10.1038/s41564-020-0682-4. PubMed PMID: 32042131; PubMed Central PMCID: PMC9335376.

Lopes Fischer, N.L.*, Naseer, N.*, Shin, S.#, and Brodsky, I.E.#: Effector-triggered immunity and pathogen sensing in metazoans. Nature Microbiology 5(1): 14-26, 2020 Notes: *equal contribution, listed in alphabetical order; #co-corresponding author.

Krummel M, Blish C, Kuhns M, Cadwell K, Oberst A, Goldrath A, Ansel KM, Chi H, O'Connell R, Wherry EJ, Pepper M. Universal Principled Review: A Community-Driven Method to Improve Peer Review. Cell. 2019 Dec 12;179(7):1441-1445. doi: 10.1016/j.cell.2019.11.029. PubMed PMID: 31835023.

Liu X, Shin S. Viewing Legionella pneumophila Pathogenesis through an Immunological Lens. J Mol Biol. 2019 Oct 4;431(21):4321-4344. doi: 10.1016/j.jmb.2019.07.028. Epub 2019 Jul 25. Review. PubMed PMID: 31351897; PubMed Central PMCID: PMC9332137.

Kuipers K, Lokken KL, Zangari T, Boyer MA, Shin S, Weiser JN. Age-related differences in IL-1 signaling and capsule serotype affect persistence of Streptococcus pneumoniae colonization. PLoS Pathog. 2018 Oct;14(10):e1007396. doi: 10.1371/journal.ppat.1007396. eCollection 2018 Oct. PubMed PMID: 30379943; PubMed Central PMCID: PMC6231672.

  • Mantegazza AR, Wynosky-Dolfi MA, Casson CN, Lefkovith AJ, Shin S, Brodsky IE, Marks MS. Increased autophagic sequestration in adaptor protein-3 deficient dendritic cells limits inflammasome activity and impairs antibacterial immunity. PLoS Pathog. 2017 Dec;13(12):e1006785. doi: 10.1371/journal.ppat.1006785. eCollection 2017 Dec. PubMed PMID: 29253868; PubMed Central PMCID: PMC5749898.

    Reyes Ruiz VM, Ramirez J, Naseer N, Palacio NM, Siddarthan IJ, Yan BM, Boyer MA, Pensinger DA, Sauer JD, Shin S. Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13242-13247. doi: 10.1073/pnas.1710433114. Epub 2017 Nov 27. PubMed PMID: 29180436; PubMed Central PMCID: PMC5740664.

    Shin S, Cherry S. A RHIM with a View: FLYing with Functional Amyloids. Immunity. 2017 Oct 17;47(4):604-606. doi: 10.1016/j.immuni.2017.10.001. PubMed PMID: 29045890.

    Casson CN*, Doerner JL*, Copenhaver AM, Ramirez J, Holmgren AM, Boyer MA, Siddarthan IJ, Rouhanifard SH, Raj A, Shin S. Neutrophils and Ly6Chi monocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection. PLoS Pathog. 2017 Apr;13(4):e1006309. doi: 10.1371/journal.ppat.1006309. eCollection 2017 Apr. PubMed PMID: 28384349; PubMed Central PMCID: PMC5404877. Notes: *co-first authors; listed in alphabetical order

    Holmgren AM, McConkey CA, Shin S. Outrunning the Red Queen: bystander activation as a means of outpacing innate immune subversion by intracellular pathogens. Cell Mol Immunol. 2017 Jan;14(1):14-21. doi: 10.1038/cmi.2016.36. Epub 2016 Aug 22. Review. PubMed PMID: 27545071; PubMed Central PMCID: PMC5214943.

    Shin S. Dual pH/Activity Probes Expand the Cathepsin Toolkit. Cell Chem Biol. 2016 Aug 18;23(8):891-2. doi: 10.1016/j.chembiol.2016.08.004. PubMed PMID: 27541194.

    Bradley WP, Boyer MA, Nguyen HT, Birdwell LD, Yu J, Ribeiro JM, Weiss SR, Zamboni DS, Roy CR, Shin S. Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse Macrophages. Infect Immun. 2016 Apr;84(4):998-1015. doi: 10.1128/IAI.01536-15. Print 2016 Apr. PubMed PMID: 26787725; PubMed Central PMCID: PMC4807492.

    Shin S, Argon Y. Stressed-Out Endoplasmic Reticulum Inflames the Mitochondria. Immunity. 2015 Sep 15;43(3):409-11. doi: 10.1016/j.immuni.2015.08.027. PubMed PMID: 26377891.

    Copenhaver AM, Casson CN, Nguyen HT, Duda MM, Shin S. IL-1R signaling enables bystander cells to overcome bacterial blockade of host protein synthesis. Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7557-62. doi: 10.1073/pnas.1501289112. Epub 2015 Jun 1. PubMed PMID: 26034289; PubMed Central PMCID: PMC4475993.

    Casson CN, Yu J, Reyes VM, Taschuk FO, Yadav A, Copenhaver AM, Nguyen HT, Collman RG, Shin S. Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6688-93. doi: 10.1073/pnas.1421699112. Epub 2015 May 11. PubMed PMID: 25964352; PubMed Central PMCID: PMC4450384.

    Shin S, Brodsky IE. The inflammasome: Learning from bacterial evasion strategies. Semin Immunol. 2015 Mar;27(2):102-10. doi: 10.1016/j.smim.2015.03.006. Epub 2015 Apr 23. Review. PubMed PMID: 25914126.

    Copenhaver AM, Casson CN, Nguyen HT, Fung TC, Duda MM, Roy CR, Shin S. Alveolar macrophages and neutrophils are the primary reservoirs for Legionella pneumophila and mediate cytosolic surveillance of type IV secretion. Infect Immun. 2014 Oct;82(10):4325-36. doi: 10.1128/IAI.01891-14. Epub 2014 Aug 4. PubMed PMID: 25092908; PubMed Central PMCID: PMC4187856.

    Philip NH, Dillon CP, Snyder AG, Fitzgerald P, Wynosky-Dolfi MA, Zwack EE, Hu B, Fitzgerald L, Mauldin EA, Copenhaver AM, Shin S, Wei L, Parker M, Zhang J, Oberst A, Green DR, Brodsky IE. Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7385-90. doi: 10.1073/pnas.1403252111. Epub 2014 May 5. PubMed PMID: 24799700; PubMed Central PMCID: PMC4034241.

    Casson CN, Shin S. Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophila. Front Cell Infect Microbiol. 2013 Dec 27;3:111. doi: 10.3389/fcimb.2013.00111. Review. PubMed PMID: 24409420; PubMed Central PMCID: PMC3873505.

    Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE*, Shin S.* Caspase-11 activation in response to bacterial secretion systems that access the host cytosol. PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6. PubMed PMID: 23762026; PubMed Central PMCID: PMC3675167. Notes: *co-corresponding authors

    Shin S, Brodsky IE. Caspase-11: the noncanonical guardian of cytosolic sanctity. Cell Host Microbe. 2013 Mar 13;13(3):243-5. doi: 10.1016/j.chom.2013.02.011. PubMed PMID: 23498948 

    Fontana MF, Shin S, Vance RE. Activation of host mitogen-activated protein kinases by secreted Legionella pneumophila effectors that inhibit host protein translation. Infect Immun. 2012 Oct;80(10):3570-5. doi: 10.1128/IAI.00557-12. Epub 2012 Jul 30. PubMed PMID: 22851749; PubMed Central PMCID: PMC3457587.

    Shin S. Innate Immunity to Intracellular Pathogens: Lessons Learned from Legionella pneumophila. Adv Appl Microbiol. 2012;79:43-71. doi: 10.1016/B978-0-12-394318-7.00003-6. PubMed PMID: 22569517.

  • Lippmann J, Müller HC, Naujoks J, Tabeling C, Shin S, Witzenrath M, Hellwig K, Kirschning CJ, Taylor GA, Barchet W, Bauer S, Suttorp N, Roy CR, Opitz B. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell Microbiol. 2011 Nov;13(11):1668-82. doi: 10.1111/j.1462-5822.2011.01646.x. Epub 2011 Aug 24. PubMed PMID: 21790939; PubMed Central PMCID: PMC3196383.

    Jensen KD*, Shin S*, Chien YH. Cutting edge: Gammadelta intraepithelial lymphocytes of the small intestine are not biased toward thymic antigens. J Immunol. 2009 Jun 15;182(12):7348-51. doi: 10.4049/jimmunol.0900465. PubMed PMID: 19494256. Notes: *equal contribution

    Nogueira CV, Lindsten T, Jamieson AM, Case CL, Shin S, Thompson CB, Roy CR. Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. PLoS Pathog. 2009 Jun;5(6):e1000478. doi: 10.1371/journal.ppat.1000478. Epub 2009 Jun 12. PubMed PMID: 19521510; PubMed Central PMCID: PMC2689937.

    Case CL, Shin S, Roy CR. Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect Immun. 2009 May;77(5):1981-91. doi: 10.1128/IAI.01382-08. Epub 2009 Feb 23. PubMed PMID: 19237518; PubMed Central PMCID: PMC2681768.

    Shin S, Case CL, Archer KA, Nogueira CV, Kobayashi KS, Flavell RA, Roy CR, Zamboni DS. Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila. PLoS Pathog. 2008 Nov;4(11):e1000220. doi: 10.1371/journal.ppat.1000220. Epub 2008 Nov 28. PubMed PMID: 19043549; PubMed Central PMCID: PMC2582680.

    Jensen KD, Su X, Shin S, Li L, Youssef S, Yamasaki S, Steinman L, Saito T, Locksley RM, Davis MM, Baumgarth N, Chien YH. Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity. 2008 Jul 18;29(1):90-100. doi: 10.1016/j.immuni.2008.04.022. Epub 2008 Jun 26. PubMed PMID: 18585064; PubMed Central PMCID: PMC2601709.

    Adams EJ, Strop P, Shin S, Chien YH, Garcia KC. An autonomous CDR3delta is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by gammadelta T cells. Nat Immunol. 2008 Jul;9(7):777-84. doi: 10.1038/ni.1620. Epub 2008 May 30. PubMed PMID: 18516039; PubMed Central PMCID: PMC2768525.

    Shin S, Roy CR. Host cell processes that influence the intracellular survival of Legionella pneumophila. Cell Microbiol. 2008 Jun;10(6):1209-20. doi: 10.1111/j.1462-5822.2008.01145.x. Epub 2008 Mar 17. Review. PubMed PMID: 18363881; NIHMSID:NIHMS336057.

    Neild AL, Shin S, Roy CR. Activated macrophages infected with Legionella inhibit T cells by means of MyD88-dependent production of prostaglandins. J Immunol. 2005 Dec 15;175(12):8181-90. doi: 10.4049/jimmunol.175.12.8181. PubMed PMID: 16339557.

    Shin S, El-Diwany R, Schaffert S, Adams EJ, Garcia KC, Pereira P, Chien YH. Antigen recognition determinants of gammadelta T cell receptors. Science. 2005 Apr 8;308(5719):252-5. doi: 10.1126/science.1106480. PubMed PMID: 15821090.

    Khakoo SI, Geller R, Shin S, Jenkins JA, Parham P. The D0 domain of KIR3D acts as a major histocompatibility complex class I binding enhancer. J Exp Med. 2002 Oct 7;196(7):911-21. doi: 10.1084/jem.20020304. PubMed PMID: 12370253; PubMed Central PMCID: PMC2194033.

    Robbins KE, Kostrikis LG, Brown TM, Anzala O, Shin S, Plummer FA, Kalish ML. Genetic analysis of human immunodeficiency virus type 1 strains in Kenya: a comparison using phylogenetic analysis and a combinatorial melting assay. AIDS Res Hum Retroviruses. 1999 Mar 1;15(4):329-35. doi: 10.1089/088922299311295. PubMed PMID: 10082116.

    Kostrikis LG, Shin S, Ho DD. Genotyping HIV-1 and HCV strains by a combinatorial DNA melting assay (COMA). Mol Med. 1998 Jul;4(7):443-53. PubMed PMID: 9713823; PubMed Central PMCID: PMC2230331.

    Bogyo M, Shin S, McMaster JS, Ploegh HL. Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes. Chem Biol. 1998 Jun;5(6):307-20. doi: 10.1016/s1074-5521(98)90169-7. PubMed PMID: 9653549.

    Shin S, Day LA. Separation and size determination of circular and linear single-stranded DNAs by alkaline agarose gel electrophoresis. Anal Biochem. 1995 Apr 10;226(2):202-6. doi: 10.1006/abio.1995.1214. PubMed PMID: 7793618.

    Kostrikis LG, Reisberg SA, Kim HY, Shin S, Day LA. C2, and unusual filamentous bacterial virus: protein sequence and conformation, DNA size and conformation, and nucleotide/subunit ratio. Biochemistry. 1995 Mar 28;34(12):4077-87. doi: 10.1021/bi00012a026. PubMed PMID: 7696272.